18 hours ago · HKU5-CoV-2 is a virus found in bats. It’s a type of coronavirus, a large group of germs that can affect mammals and birds. Some have passed from animals to humans, like SARS-CoV-2, which causes ...

1 day ago · Researchers found that HKU5-CoV-2 can bind to human ACE2 receptors, a characteristic shared with SARS-CoV-2, the virus responsible for COVID-19. The ability to interact with these receptors suggests a potential for human infection. During laboratory tests, HKU5-CoV-2 was able to infect human cell cultures in mini-organ models.

16 hours ago · HKU5-CoV-2 is a part of the HKU5 coronavirus family, which originates in bats. Since the virus possesses a furin cleavage site, a feature that enhances viral entry into cells through the ACE2 receptor, researchers believe its ability to …

21 hours ago · HKU5-CoV-2 is a newly discovered bat coronavirus that belongs to the merbecovirus subgenus, which also includes the virus responsible for Middle East respiratory syndrome (MERS).

5 days ago · However, the potential human spillover risk of animal merbecoviruses remains to be investigated. Here, we reported the discovery of HKU5-CoV lineage 2 (HKU5-CoV-2) in bats that efficiently utilize human angiotensin-converting enzyme 2 (ACE2) as a functional receptor and exhibits a broad host tropism.

21 hours ago · Known as HKU5-CoV-2, the virus also appears capable of hooking onto other versions of ACE2 in multiple different mammals, suggesting it may be capable of jumping to other species. The detection of ...

1 day ago · The scientists said that like SARS-CoV-2, the bat virus HKU5-CoV-2 contains a feature known as the furin cleavage site that helps it to enter cells via the ACE2 receptor protein on cell surfaces. In lab experiments, HKU5-CoV-2 infected human cells with high ACE2 levels in test tubes and in models of human intestines and airways.