Scotland have hope of mounting a Six Nations title challenge as they embark on a fresh campaign against Italy.While optimism has been punctured somewhat by a string of untimely injuries, Gregor Townsend’s settled squad are confident that they can build on their development over the last few years and back up big performances to challenge for a long-awaited title.

England’s third game of the 2025 Six Nations Championship will see them face Scotland at Twickenham. Scotland have won the last four Six Nations meetings against the Auld Enemy, including a 30-21 victory at Murrayfield last year.

Talking points as Scotland begin their Six Nations challenge against Italy - The Scots are looking to win their opening fixture for the fifth successive campaign.

Scotland player ratings: Scotland’ Six Nations campaign got off to a winning start with a five-try, 31-19 bonus-point victory over Italy at Murrayfield.

Jon Newcombe runs the rule over Saturday's Six Nations action, including a mouthwatering clash between Ireland and England in Dublin.

Scotland will be out for revenge on Saturday as they take on Italy at Murrayfield in their opening fixture of the 2025 Six Nations. Last year's encounter between these two sides saw the Italians secure their first Six Nations home win in 11 years,

Kick-off time today, TV channel, live stream, team news, lineups, h2h - Scots reeling from Sione Tuipulotu injury blow ahead of Azzurri’s visit to Murrayfield