Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...

Get Instant Summarized Text (Gist) Two molecular control factors, GPATCH1 and DHX35, are crucial for ensuring the accuracy of mRNA splicing, a process essential for protein synthesis. These ...

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

A new study published in the International Journal of Molecular Sciences suggests that the cannabinoid cannabinerol (CBNR) ...

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and ...

Cleft lip and cleft palate are among the most common birth defects, occurring in about one in 1,050 births in the United ...

Mutations (blue) in U2 snRNA cause a neurodevelopmental disorder about one-fifth as common as the RNU4-2/ReNU disorder, which ...

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and ...

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies. CDK4/6 inhibitors show promise ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA—a prerequisite for protein synthesis in the cell. The poorly ...

A seminal study from researchers at the Icahn School of Medicine at Mount Sinai and their collaborators in the United Kingdom, Belgium, Spain, the Netherlands, and Iceland has uncovered a new genetic ...