The four No. 1 seeds in the NCAA Tournament escaped the second weekend of the Big Dance and are heading to the Final Four to cap one of the chalkiest NCAA Tournaments ever. It's the first time since 2008 and just the second time since the field expanded to 64 teams in 1985 that all four No. 1 seeds are still standing at this juncture.

The SportsLine Projection Model has revealed its Houston Cougars vs. Duke Blue Devils picks for the Final Four of the 2025 NCAA Tournament on Saturday

Just as they did in the 2024 NCAA Tournament, Duke and Houston will play in March Madness this season. This time it’s in the Final Four national semifinals at San Antonio.

Auburn and Florida will get the Final Four started on Saturday at 6:09 ET. The Duke-Houston matchup will be roughly 30 minutes after the conclusion of game one. Both games will take place at the Alamodome in San Antonio, Texas, and they will both be airing on CBS.

The Duke Blue Devils face the Houston Cougars in the Final Four of the men’s NCAA Tournament at the Alamodome in San Antonio, Texas, on Saturday, April 5, 2025.

Cooper Flagg and Duke basketball are playing Alabama in the Elite Eight of March Madness. Follow live score updates.

For the 18th time in program history and the first time under head coach Jon Scheyer, the top-seeded Duke Blue Devils will play in the Final Four after they ousted No. 2 Alabama on Saturday night.

The Volunteers were seeking their first trip to the Final Four in men's basketball history, and have an uphill climb after setting a record they'd like to forget.

A fifth straight trip to the Final Four is on the line for the Gamecocks. Duke is back in the Elight Eight for the first time since 2013.

Houston basketball is prepared for the challenge in its Final Four matchup against Duke, and it's going to be a classic showdown.