We first showed that production of TNF, IL-6 and Cox-2 were supressed by a post-transcriptional ... 7ng/ml mycolactone is sufficient to deplete thrombomodulin from the surface of the cells in under ...

Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host response to infection. During sepsis, the coagulation cascade is ...

Mounting evidence indicates that nuclear receptors play a critical regulatory role in platelet pathophysiology and thrombotic disorders. Although NR4A (the nuclear receptor subfamily 4 group A) plays ...

Both thrombomodulin (TM) and factor XIII-A (FXIII-A ... as per the instructions of the manufacturer. The serum levels of TNF-α and IL-6 in murine were measured by TNF-α ELISA kit (CSB-E04741, Wuhan ...

Department of Cardiology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong ...

Fat necrosis refers to dead or damaged breast tissue that often manifests as a noncancerous lump under the skin. In most cases, these lumps go away on their own and don’t return. Fat necrosis of ...

The strength of the evidence is solid and has been improved in the revised version. Tissue necrosis is a devastating complication for many human diseases and injuries. Unfortunately, our understanding ...

Heat shock protein (HSP) 40 has emerged as a key factor in both innate and adaptive immunity, whereas the role of HLJ1, a molecular chaperone in HSP40 family, in modulating endotoxin-induced sepsis ...