Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...
Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA ...
Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, ...
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...
as it offers both a refined predictive model and a new tool to designing RNA sequences for targeted splicing outcomes. Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific ...
The authors propose a transformer-based model for the prediction of condition - or tissue-specific alternative splicing and demonstrate its utility in the design of RNAs with desired splicing outcomes ...
This month's cover highlights the article Immune cells adapt to confined environments in vivo to optimise nuclear plasticity for migration by Helen Weavers and Tua Karling. The cover features confocal ...
Emerging evidence suggests that some variants, which are described as missense, synonymous or nonsense variants in the literature or databases, may be deleterious by affecting the pre-mRNA splicing ...
RNA quality control is the active process by ... and TENT5A/C substrate mRNAs are highlighted in the paper. Proper splicing requires efficient spliceosome assembly. Here the authors reveal that ...
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