The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different ...

UCSF scientists find a trove of new targets for cancer immunotherapy in cancer’s unique version of RNA splicing.

Starting a business in the United States involves a number of different steps spanning legal considerations, market research, creating a business plan, securing funding, and developing a marketing ...

Seven years ago, global pop phenomenon Jennie became the first member of the K-pop group Blackpink to release solo music. On Friday, she becomes the latest to drop a debut solo studio album ...

Our aim was to evaluate the performance of a set of commonly used splicing in silico tools comparing the predictions against RNA in vitro results. This was done for natural splice sites of clinically ...

Moreover, NGS technologies require a PCR amplification step, and as such, they are typically blind to DNA or RNA modifications (Novoa et al., 2017). For each step, the workflow extracts metrics which ...

In particular, RNA-targeting CRISPR-Cas13 proteins are promising single-effector systems to regulate target mRNAs without altering genomic DNA, yet the current Cas13 systems are restrained by ...

Government supporters argue that the crackdown on conservative opponents was necessary, because such steps would have been strongly opposed by hardliners and slowed the country’s progress.