Mark Davis and colleagues gave mice naked synthetic siRNAs against fatty acid synthase (FAS), c-MYC, or luciferase, through intraperitoneal injections or via the tail vein using either low-pressure (1 ...

Tail vein injection, as well as intratumoral injection, of the ligand-liposomes with a reporter gene in nude mice bearing human breast cancer or SCCHN xenografts, resulted in a significantly ...