The movie is set in its own universe, and director Matt Shakman says that universe is pretty disconnected from the rest of the MCU.

T here was a time when it seemed we'd never see the Fantastic Four cross paths with other Marvel Cinematic Universe ...

First Steps focus on family just became clearer after a new reveal from CinemaCon that could hint at how the Multiverse ends.

There’s no Easter eggs. There’s no running into Iron Man or whatever. They’re it, in this universe. I love the interconnected Marvel Universe, but we get to do something so new and so different.