In pulmonary hypertension, a combination of metabolic and mechanical dysfunction leads to irreversible vascular damage.

Pulmonary arterial hypertension (PAH) is a rare form of pulmonary hypertension. It occurs because progressive vascular ...

In April 2025, Actelion announced a study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the ...

Pulmonary hypertension is a common consequence ... PH is a common consequence of ILD because of vascular and parenchymal remodeling, with the highest rate seen among individuals who have ...

The hyperproliferation of smooth muscle cells and deposition of collagen in the pulmonary artery are among the primary characteristics of pulmonary hypertension (PH). These processes contribute to ...

Pulmonary hypertension (PH) is a life-threatening and progressive ... is critically involved in the pathogenesis of PH by controlling pulmonary vascular tone, arterial remodeling, and associated lung ...

Background: Pulmonary arterial hypertension (PAH) is a severe disease marked by the remodeling of arteries due to the abnormal growth of vascular cells, including pulmonary arterial smooth muscle ...

Pulmonary vascular remodeling is a progressive pathological process characterized ... cells from healthy controls and individuals with idiopathic pulmonary arterial hypertension (IPAH), our ...