Background and Objective: Narcotic analgesics such as hydromorphone undergo an extensive first-pass effect resulting in a low systemic bioavailability following oral administration. Alternative ...

Under the new plans, Victorian healthcare workers will supervise a select group of heroin users to inject the powerful drug hydromorphone at a new community health hub to be built opposite ...

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In moderate to severe pain from blunt trauma, sublingual sufentanil was not more effective than standard care in reducing pain at 30 minutes.

The health minister says the "significant" change to end the take-home model will be difficult for some but is designed to reduce the criminal diversion of prescribed alternatives.

The B.C. government is making changes to its safer supply program that will require patients to take their doses of medications such as hydromorphone in the presence of a health care worker.

Juls Budau takes her prescription hydromorphone three times per day: a half tablet shortly after waking up, while making her morning coffee; another in the afternoon, while wrapping up work ...

Reidenberg et al. [15] measured hydromorphone concentrations in serum samples from patients treated for chronic severe pain and estimated the minimum effective plasma concentration at ...