Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Dr. Andrés Hidalgo has discovered a specialized population of neutrophils in the skin that produce extracellular matrix, ...

Australian food scientists have reclassified dietary fibers—beyond just soluble and insoluble—to better guide nutritional ...

Extracellular vesicles play a vital role in cell biology, modulating communication and signaling, with potential applications in diagnostics and therapeutics.

Extracellular vesicles (EVs ... and inhibiting the expression of genes related to cartilage matrix synthesis in chondrocytes (such as COL2A1 and ACAN). Furthermore, they exert regulatory influence ...

The latter allows cells to anchor to the extracellular matrix, a network of proteins surrounding them. AP2A1 and integrin β1 move together along stress fibers. Integrin β1 strengthens cell adhesion to ...

Due to the inherent nature of their spreading modalities, these proteins are exposed to components of the extracellular matrix (ECM), including glycans, proteases and core matrix proteins. These ECM ...