Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

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We also found that some genes showed differential expression or alternative splicing, which may be associated with different ... for 30 min at 37°C to remove residual DNA. The quality of the RNA was ...

CCK-8 assay kit (Beyotime Institute of Biotechnology ... AS analysis displayed no differences between PCOS and control groups regarding the alternative splicing type or gene numbers. Usually, PCOS is ...

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Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of ...