imdb.com18d
Splice: Why The Sci-Fi Horror Movie's Sequel Never Happened
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eLife21d
Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in male obese mice
Quantitative analysis of immunoblots was performed (F’). G-G’. Splicing of XBP1 mRNA was analyzed from eWAT of DIO mice treated with vehicle or STF by RT-PCR and resolved by agarose gel ...
The EMBO Journal21d
Chaperone-mediated autophagy regulates the metastatic state of mesenchymal tumors
Combined, these findings show that CMA displays a broad targetability on multiple steps of the EMT process and indicate a substantial role of CMA in regulating the stability of pro-metastatic and ...
Frontiers26d
Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation
XBP1 mRNA splicing was detected by reverse transcription (RT)-PCR ... After activation, the supernatants were collected for cytokine detection, cells were washed twice and media was changed for ...
Frontiers28d
Cytokine concentration in peripheral blood of patients with colorectal cancer
Introduction: The role of tumour secretory cytokines and peripheral circulatory cytokines in tumour progression has received increasing attention; however, the role of tumour-related inflammatory ...
eLife5y
High fat diet induces microbiota-dependent silencing of enteroendocrine cells
Enteroendocrine cells (EECs) are specialized sensory cells in the intestinal epithelium that sense and transduce nutrient information. Consumption of dietary fat contributes to metabolic disorders, ...