Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that starts ...

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Cancer: This loss of motivation doesn't just deepen patients' suffering, it isolates them from family and friends. Because ...

A new study published in npj Metabolic Health and Disease suggests that eating more ultra-processed foods may not only increase the risk of obesity and poor metabolic health, but could also be ...

New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

High intake of ultra-processed foods is linked to adverse metabolic health and microstructural brain changes in regions that ...

The developmental progress from daredevil teen to risk-averse senior is more complex than we thought, according to a new study that identified changing relationships between neural structures related ...

Summary: New research uncovers how dopamine in the ventral shell of the nucleus accumbens (vsNAc) governs the sexual behavior sequence in male mice, from sniffing to ejaculation. Using fiber ...