Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Natural "off switch" could slow or even reverse the growth of aggressive tumors.

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

A study reveals how cancer disrupts RNA splicing and presents a potential therapy using antisense oligonucleotides to target ...

Avidity Biosciences, Inc.'s innovative AOC platform and promising clinical programs make it a high-risk, high-reward ...

MRNA technology is facing growing doubts among Republicans. This is a KFF Health News story. Researchers racing to develop bird flu vaccines for humans have turned to a cutting-edge technology ...

Vaccine skeptics have long-since leveraged the rapid roll out of mRNA vaccines to add fuel to heated arguments surrounding vaccine safety. As a result, a growing share of the public is wary of ...

The disorder is caused by a mutation of this DMPK gene causing mis-splicing of genes. In essence, the mutation of this gene causes improper mRNA splicing. Thus, the goal of DYNE-101 is to knock ...

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film. By selecting which scenes to keep and which to leave out, ...