Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

A team of researchers has identified a mechanism that regulates the production of two different proteins from the same gene.

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different ...

RNA quality control is the active process by ... and TENT5A/C substrate mRNAs are highlighted in the paper. Proper splicing requires efficient spliceosome assembly. Here the authors reveal that ...