This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

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MKs exhibit cellular diversity, with subpopulations such as platelet-generating MKs, HSC niche MKs, and immune MKs, each with unique functional attributes. HSC niche MKs modulate HSC quiescence ...

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These strategies leverage the tumor-homing tendencies of macrophages to locally deliver therapeutic cargo and induce cytotoxic activity within the tumor niche. Although CAR-M-based approaches have ...

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