EVM14 received U.S. FDA clearance for its IND application, becoming Everest's first internally discovered program, and the first mRNA therapeutic cancer vaccine to be cleared for global clinical ...

23 Cre was activated by intraperitoneal injections of tamoxifen at a dose of 1 mg/d for 5 subsequent days at the age of 4 weeks. Control animals were treated with corn oil, the solvent of tamoxifen.

Euthanasia by CO2 and cervical dislocation. Physical handling (lifting and transporting mice), restraint, and earmarking. Injections (IP, SC) and blood sampling (vena saphena, tail vein). Dissection ...

The researchers used fiber photometry systems to detect neurotransmitters, which involved injecting the mice with fluorescent ...

By replacing the defective gene associated with Dravet syndrome in mice, scientists successfully alleviated symptoms without side effects.

This month marks the fifth anniversary of the pandemic. We asked students how their lives are different today because of it. By The Learning Network President Trump abruptly stopped providing ...

Regenerative medicine is the branch of medicine that develops methods to regrow, repair or replace damaged or diseased cells, organs or tissues. Regenerative medicine includes the generation and ...

Here the authors use PET imaging and demonstrate transient expression of the vaccine antigen in the injection site and draining lymph nodes in mice and non-human primates.

Preclinical data with the investigational gene therapy INS1202 show improvements in survival and motor performance in ALS.

Drug A killed all the rats, mice and dogs. Drug B killed all the dogs ... approach of the experimenter to each experiment. John P Gluck has suggested that this is often lacking: The lack of ...

Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, United States Department of Immunology, Department of ...