Study design Experimental study utilizing a standardized Balb C mouse model. Objectives Evaluate histological ... 15 The groups were allocated as follows: Group 1: A single injection of 4 × 105/40 µL ...

Change from baseline in paw thickness was determined daily by dial calipers, and an average change in ankle thickness was determined for each mouse from the two hind paw measurements. Mice were ...

This includes comorbidities (e.g., diabetes, thyroid disorders), frequency of injection, cost, and/or age. Desired weight loss can also help narrow down the choice, as some options have a greater ...

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Chemotherapy-induced neuropathy was induced in mice by intraplantar injection of oxaliplatin into the left hind paw (Deuis et al., 2013; MacDonald et al., 2021). Oxaliplatin was made up to a dose of ...

Researchers have now developed a technology that can be used to test around 25 antibodies simultaneously in a single mouse. This should not only speed up the research and development pipeline for ...