This study advances our understanding of the molecular mechanisms underlying hair follicle regeneration and offers new insights into how stem cell survival and tissue regeneration are orchestrated,' ...

The MCL-1 protein is essential for hair follicle stem cell survival and regrowth, preventing excessive cell death Blocking MCL-1 in mice led to hair loss, suggesting its potential role in treating ...

Skin moles that sprout thick, long hairs produce signaling molecules that stimulate hair follicle stem cells to initiate new hair growth. This discovery may make baldness a thing of the past. A series ...

"Acute MCL‑1 deletion rapidly depletes activated hair follicle stem cells and completely blocks depilation‑induced hair regeneration in adult mice, while quiescent hair follicle stem cells remain ...

More information: Hui San Chin et al, MCL‑1 safeguards activated hair follicle stem cells to enable adult hair regeneration, Nature Communications (2025). DOI: 10.1038/s41467-025-58150-5 ...