Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Researchers have identified in a new study that oral infigratinib, an FGFR1-3 selective tyrosine kinase inhibitor, improves ...

Pluripotent stem cells are cells that have the capacity to self-renew by dividing and to develop into the three primary germ cell layers of the early embryo and therefore into all cells of the ...

Bone development is the formation and growth of bones. New bone is formed by the action of specialised cells called osteoblasts and osteoclasts, either by directly laying down bone tissue into ...

5 Department of Cell Biology, New York University School of Medicine, New York, New York, USA Correspondence to Professor Xiu-Ping Yu, Institute of Pathogenic Biology, Shandong University School of ...

There is increasing evidence that T lymphocytes play a key role in controlling endogenous regeneration. Regeneration appears to be impaired in case of local accumulation of CD8+ effector T cells (T ...

Heterotopic ossification happens when bone grows outside of its normal location and into the surrounding soft tissues of your body. When this happens, the pieces of bone that develop are called ...

1 Department of Sensory and Motor System Medicine, The University of Tokyo Graduate School of Medicine, Tokyo, Japan Background Ossification of the posterior longitudinal ligament (OPLL) of the spine ...

Monocytes and macrophages are innate immune cells with diverse functions ranging from phagocytosis of microorganisms to forming a bridge with the adaptive immune system. A lesser-known attribute of ...

2 Biomedical Institute for Pioneering Investigation via Convergence and Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing, China 3 Beijing Advanced Innovation ...