New research reports that primary human dermal fibroblasts seeded into a three-dimensional biodegradable matrix can differentiate in vitro into osteoblasts and chondrocytes, and form three ...

“It doesn’t surprise me per se, because the theory was always there.” Experiments in the 1960s had revealed that the fibroblast-containing dermal compartment of the skin determines the identity of the ...

More information: Françoise Boismal et al, Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging, Aging (2024). DOI: 10. ...

Traditionally, fibroblasts—specialized supporting cells within the dermis—have been believed to play a key role in producing collagen. In humans, collagen is formed before and after birth.

Alternatively, we aim to induce chondrogenic stem / progenitor cells directly from mouse dermal fibroblast culture by employing methods of directed reprogramming. Induced cells could produce ...

My postdoctoral research focused on dissecting the plasticity and tissue scale behaviour of skin dermal fibroblast lineages during development, homoeostasis and wound healing. In 2018 I was awarded an ...