Common catalyst works by cycling between two different forms, upending a long-held supposition
The process of catalysis—in which a material speeds up a chemical reaction—is crucial to the production of many of the chemicals used in our everyday lives. But even though these catalytic processes ...
Adipocyte-hepatocyte signaling mechanism uncovered in endoplasmic reticulum stress response
The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...
eLife4d
Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations
This important study shows, for the first time, the structure and snapshots of the dynamics of the full-length soluble Angiotensin-I converting enzyme dimer. The combination of structural and ...
Science Daily4d
Omega-6 fatty acid promotes the growth of an aggressive type of breast cancer, study finds
Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat 'triple ...
Rutgers University4d
Researcher Uncovers How Dietary Fat May Fuel Cancer Growth
A Rutgers biochemistry professor explains how omega-6 fatty acids found in Western diets can activate cellular growth ...
AHA/ASA Journals4d
Lymphatic Endothelial Branched-Chain Amino Acid Catabolic Defects Undermine Cardiac Lymphatic Integrity and Drive HFpEF
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but ...