Annie (Kristen Wiig), is a maid of honor whose life unravels as she leads her best friend Lillian (Maya Rudolph) and a group of colorful bridesmaids (Rose Byrne, Melissa McCarthy, Wendi McLendon ...

Four very different women, best friends during high school many years earlier, gather in the small town where they grew up for a reunion as bridesmaids in preparation for a wedding for a fifth friend.