Alcohol is a part of many people’s lives and can be hard to avoid. However, drinking more than the recommended amount can be harmful to your heart and general health. While there is no completely safe ...

"ALPK2-overexpression suppressed progression of diastolic dysfunction. In addition, it improved lung weight, which is often used as an index of heart failure," Yoshida summarized. "HFpEF is a ...

The immune response to infections may become dysregulated and promote myocardial damage contributing to heart failure (HF). We examined the relationship between infection‐related hospitalization (IRH) ...

Background Early heart failure (HF) diagnosis is crucial to ensure that optimal guideline-directed medical therapy (GDMT) is administered to reduce morbidity and mortality. Limited access to ...

Normal or mildly abnormal LV systolic function (LV EF >50% or LV end-diastolic volume ... Valsartan Heart Failure Trial; VALIANT: Valsartan In Acute Myocardial Infarction Trial.

JK-07 is under clinical development by Salubris Biotherapeutics and currently in Phase II for Diastolic Heart Failure (HFpEF). According to GlobalData, Phase II drugs for Diastolic Heart Failure ...

Ziltivekimab is under clinical development by Novo Nordisk and currently in Phase III for Diastolic Heart Failure (HFpEF). According to GlobalData, Phase III drugs for Diastolic Heart Failure (HFpEF) ...

The integrative physiology of the left ventricle and systemic circulation is fundamental to our understanding of advanced heart failure and cardiogenic shock. In simplest terms, any increase in aortic ...

What Is Diastolic Heart Failure? A classic example of diastolic heart failure (HF) is a little old lady with systolic hypertension who presents with increasing breathlessness and, on examination ...