It's the second time this week and the fifth time since the start of last season the Twins have lost in walk-off fashion at Progressive Field.

After the Twins took a 3-2 lead in the 10th on a sacrifice fly by Johan Bride, the Guardians struck for two runs in the bottom of the 10th to win it. Ramirez drove in automatic runner Gabriel Arias to tie the score and pinch-hitter Martinez drove in Ramirez with the winning run on a single to right.

José Ramírez became the first player in Cleveland franchise history to reach 250 career homers and 250 steals and then scored the winning run in the 10th inning as the Guardians rallied for a 4-3 victory over the Minnesota Twins.