Santander has been dealing with some injury issues this season, most notably his left shoulder that has caused some repeated problems throughout the year. Shortly after his removal, the Blue Jays announced an update on Santander, and it was a different injury this time that caused his early exit.

Daulton Varsho hit a grand slam in a seven-run eighth inning and the Toronto Blue Jays routed the San Diego Padres 14-0 on Wednesday night

By losing 14-0 to the Toronto Blue Jays on Wednesday, the San Diego Padres' five-game losing streak reached a low point not seen since the franchise's origins.

MLB player prop bets and odds for Fernando Gabriel Tatís on Wednesday, May 21, 2025, as the San Diego Padres take on the Toronto Blue Jays.

The Toronto Blue Jays likely will need more than three hits on Wednesday against the visiting San Diego Padres if they want to clinch a series victory.

Anthony Santander and Vladimir Guerrero Jr. homered, Chris Bassitt and three relievers combined on a five-hitter and the Toronto Blue Jays beat the San Diego Padres 3-0.