A programmable function in graphics cards that offers a programmer flexibility in rendering an image. The vertex shader is used to transform the attributes of vertices (points of a triangle ...

For a quadratic equation of the form \(y = k{(x - a)^2} + b\), the following diagram shows the main properties: If k > 0, the vertex is a minimum turning point If k < 0, the vertex is a maximum ...

Out of six evaluable patients on that dose, four achieved remission and stable kidney function. A higher 240 mg dose achieved similar results. Vertex’s move for Alpine marks a turnaround in the ...

Data from the studies, released in February 2024, demonstrated a strong benefit-risk profile and the ability to deliver greater restoration of CFTR function than even Trikafta. Vertex has also ...

A new EMA approval has expanded the use of Vertex Pharma’s cystic fibrosis ... or one F508del copy and one of 14 other so-called “minimal function” mutations in CFTR. The new EU approval ...

Two types of drugs improve CFTR function. Correctors bind to the protein and help it fold into the proper shape. Potentiators open channels of the protein. Vertex’s drugs combine both mechanisms ...