In addition to consensus sequences at their splice sites, eukaryotic genes with long introns also contain exonic splicing enhancers (ESEs). These sequences, which help position the splicing ...

Alternative splicing plays a pivotal role in defining cell phenotypes and physiology in multicellular eukaryotes, often distinguishing between cell types more accurately than gene expression. 1 During ...

Alternative splicing of pre-mRNAs contributes to the diversity of proteins in eukaryotes. Cells respond to signals from the environment through changes in gene expression and protein activity ...

In most eukaryotic cells, two types of spliceosome ... involved in different stages of the splicing process. The minor spliceosome has a similar architecture, but its main building blocks are ...

In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns ...

During his undergraduate degree, he worked on uncovering the effects of mutations on splicing in eukaryotes. He was also a part of an iGEM team that designed a gene-editing phage therapy for ...

Protein synthesis refers to the process by which cells construct proteins. It's a fundamental cellular mechanism for all living organisms, as proteins carry out enzymatic activities, structural ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...