"The different and more complex architecture allows the U11 snRNP to specifically identify its rare substrates in the vast RNA sequence landscape ... needed before the splicing reaction concludes.

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film.

“The different and more complex architecture allows the U11 snRNP to specifically identify its rare substrates in the vast RNA sequence landscape of every ... At least a dozen other steps are needed ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms.

EMBL Grenoble Group Leader Wojciech Galej, who has been working on pre-mRNA splicing machinery ... allows the U11 snRNP to specifically identify its rare substrates in the vast RNA sequence ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq ...

Hamilton, S.L., Cooper, T.A. (2015) The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure ... Goo, Y.H. and Cooper, T.A. (2009) CUGBP2 directly interacts with U2 17S ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns ...