The pulmonary vasculature is the exclusive target of disease in PPH, although its pathogenesis remains ... PPH associated with pulmonary arterial hypertension include collagen vascular disease ...

These animals develop cirrhosis, portal hypertension, and HPS at 4–5 ... NO. NO plays a central role in the pathophysiology of systemic and splanchnic vasodilation in cirrhosis.

In the subpopulation with combined pre- and post-capillary pulmonary hypertension (“CpcPH”) who have an ... which most strongly matches the more severe pathophysiology of patients with CpcPH. “We are ...

Published in the Journal of the American Heart Association, the study showcases the potential of AI-powered heart sound analysis to transform early detection and management of pulmonary hypertension.