Unfortunately, in up to 30–40% of patients that chronically consume opioids, opioid-induced hyperalgesia occurs. [59] This condition refers to a generalized and increasing pain sensitivity that ...

However, the therapeutic considerations, especially when dealing with elderly patients with limited functional status and associated comorbidities, may be much more complex. This retrospective ...

joint pain, and rheumatoid arthritis are becoming more common, especially among the elderly. .Cold pain therapy provides an effective, non-invasive approach to managing inflammation and pain ...