Control mice were injected with aqueous vaccine using a 26.5-gauge needle. The subcutaneous injection was given in the scruff of the neck and the intramuscular injection was made in the upper thigh.

To further explore the consequences of IL-1 blockade, the investigators developed a new acute gout model by use of intra-articular injection of MSU crystals into the ankle joint of mice.

In the study, published in Nature Cardiovascular Research, mice with heart attacks were ... lab results led to a clinical ...