Therapeutically targeting this pathway could potentially enhance the ... suggesting that the cytokine may play an important role in TLS formation. To test this, they compared mouse models of ...

This article focuses on the anti-TNF therapies and the current challenges with monoclonal antibody therapies, discusses the innovative strategies targeting cytokine pathways to decrease ...

Targeting JAKs is thought to help suppress overactive cytokine pathways, reducing inflammation — and, as a result, has been used to treat several systemic immune-related inflammatory diseases ...

A cytokine storm is a severe immune response ... These chemicals stimulate cell pathways and allow for communication between cells. Cytokines essentially signal the immune system to start doing ...

The cytokine IL-33 and ILC2 immune cells are critical ... uncovering a new TLS-creating pathway. Engineering an IL-33 drug to boost TLSs The researchers then wondered if this pathway could be ...

Understanding how genes that encode for cytokine receptors influence the responsiveness of immunocytes and keratinocytes—including complex interactions mediated by T H 1 and T H 17 pathways ...