Learn about the increased pressure in the portal vein, its causes like cirrhosis, and resulting complications such as ...

Treatment for portal hypertension in patients with cirrhosis is based on the use of β-blockers with or without organic nitrates; however, these agents are effective in less than 50% of patients ...

Medically reviewed by Jay N. Yepuri, MD Metabolic dysfunction-associated fatty liver disease (MAFLD) occurs when excess fat builds up in the liver. MAFLD can progress to metabolic ...

Portal hypertension may not be associated with any clinical abnormalities but is usually accompanied by splenomegaly, esophageal varices, ascites or symptoms resulting from shunting of venous ...

Studies show that the progression of liver disease is strongly associated with alterations in the hepatic vascular system, such as portal hypertension (PH) in cirrhosis, which results from ...

and in groups of patients with nonalcoholic cirrhosis, whereas it was ineffective in patients with class B or C portal hypertension. [15] Another two interesting studies are reported in the review ...

NORCROSS, Ga., March 31, 2025 (GLOBE NEWSWIRE) -- Galectin Therapeutics, Inc. (NASDAQ: GALT), the leading developer of therapeutics that target galectin proteins, today reported financial results and ...

Thus, screening all patients with cirrhosis with this technique to ... and grading of esophageal varices in patients with portal hypertension. The results of the pilot studies varied.

Joel Lewis, Chief Executive Officer and President of Galectin Therapeutics (GALT), said “In the U.S. approximately 5 million adults are ...

Background: It is currently recommended that all patients with liver cirrhosis undergo upper gastrointestinal endoscopy (UGIE) to identify those who have large esophageal varices (LEVx ...