Ms. Psaki, 46, will host a show at 9 p.m. Tuesday through Friday, replacing Alex Wagner, a longtime political journalist who has anchored that hour since 2022, according to a memo to staff from Rebecca Kutler, MSNBC’s president. Ms. Wagner will remain at MSNBC as an on-air correspondent.

After Joy Reid’s show, ‘The ReidOut,’ was canceled by the network, MSNBC has moved Jen and other TV hosts to new time slots.

Jen Psaki, the former Biden White House press secretary who has become a favorite at MSNBC since joining in 2023, will get even more screen time in front of viewers in April when she takes over the network’s 9 p.